Douglas R. Denney
Ph.D., 1970, University of Washington
Research Areas: Clinical Psychology
Research Professor of Neurology (courtesy appointment)
Research Professor of Psychiatry (courtesy appointment)
- Related Links
- Clinical Psychology Program
Although trained as a clinical psychologist, for most of my career my interests have centered on biological psychology. I have long believed that the field of psychology is best served by aligning itself with the compelling progress occurring in our understanding of the human nervous system. My teaching has been concerned primarily with what might be called "clinical neuroscience", the biological bases of various neurological and psychiatric disorders. Two subfields of clinical neuroscience having obvious relevance to psychologists are neuropsychology and psychopharmacology. My teaching provides students with introductions to both of these areas.
My recent research has centered on multiple sclerosis. I have published papers focusing on depression and fatigue in conjunction with this disease, and these features of multiple sclerosis continue to capture my attention. However, my principal interest centers on cognitive impairment in MS. In general, this latter area of research has attempted to answer questions concerning both "what" and "why." What is the nature of the cognitive deficits associated with MS? Why do some patients have substantial cognitive impairment with their disease while others have little or no impairment - even though their levels of physical disability may be the same?
I believe we have made substantial progress is understanding the nature of cognitive deficits in MS. Why such deficits are so severe in some patients and virtually absent in others remains at present a fascinating enigma.
Lynch, S. G., Denney, D. R., & Parmenter, B. A. (2005). The association between cognitive impairment and physical disability in multiple sclerosis. Multiple Sclerosis, 11, 469-476.
Parmenter, B. A., Denney, D. R., Lynch, S. G., Middleton, L. S., & Harlan, L. M. (2007). Cognitive impairment in patients with multiple sclerosis: Association with the APOE gene and promoter polymorphisms. Multiple Sclerosis, 13, 25-32.
Denney, D. R., Lynch, S. G., & Parmenter, B. A. (2008). A 3-year longitudinal study of cognitive impairment in patients with primary progressive multiple sclerosis: Speed matters. Journal of the Neurological Sciences, 267, 129-136.
Denney D. R., & Lynch, S. G. (2009). The impact of multiple sclerosis on patients’ performance on the Stroop Test: Processing speed vs. interference. Journal of the International Neuropsychological Society, 15, 451-458.
Bodling, A. M., Denney, D. R., & Lynch, S. G. (2009). Cognitive aging in patients with multiple sclerosis: A cross-sectional analysis of speeded processing. Archives of Clinical Neuropsychology, 24, 761-767.
Denney, D. R., Gallagher, K. S., & Lynch, S. G. (2011). Deficits in processing speed in patients with multiple sclerosis: Evidence from explicitly-timed and covertly-timed measures. Archives of Clinical Neuropsychology, 26, 110-119.
Choi, I.-Y., Lee, S.-P., Denney, D. R., & Lynch, S. G. (2011). Lower levels of glutathione (GSH) in the brains of secondary progressive multiple sclerosis patients measured by 1H magnetic resonance chemical shift imaging at 3 T. Multiple Sclerosis Journal, 17, 289-296.